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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA RBM6 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA RGS10 GDSC1000 pan-cancer AAC 0.12 0.0002
mRNA LTBR CTRPv2 pan-cancer AAC -0.16 0.0002
mRNA LAMP1 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA SOX14 GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA GGA2 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA MAP3K4 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA PGAM2 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA KDM4C CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA THAP9 CTRPv2 pan-cancer AAC 0.14 0.0002
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