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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA DNASE1 GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA SLC7A3 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA TRABD CTRPv2 pan-cancer AAC 0.16 0.0002
mRNA MSH6 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA FXYD6 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA APOBEC3G GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA PINK1 CTRPv2 pan-cancer AAC -0.15 0.0002
mRNA SLC12A2 GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA NLRP11 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA ZFPL1 CTRPv2 pan-cancer AAC -0.14 0.0002
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