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SN-38

Synonyms

SourcesNames Used
GDSC1000, CTRPv2SN-38
PharmacoGx SN-38

External IDs

DatabaseIdentifier
Smiles: CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Inchikey: FJHBVJOVLFPMQE-QFIPXVFZSA-N
Pubchem: 104842

Annotated Targets

TOP1

FDA Approval Status

Not Approved
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Top molecular features associated with response to SN-38


Feature TypeStandardized
Nominal ANOVA
mRNA PGP GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA GNPAT CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA DUSP3 CTRPv2 pan-cancer AAC -0.15 0.0002
mRNA KDM8 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA TPRG1L CTRPv2 pan-cancer AAC -0.15 0.0002
mRNA CSNK1G2 CTRPv2 pan-cancer AAC 0.15 0.0002
mRNA ZNF594 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA SLC35F6 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA CHP1 CTRPv2 pan-cancer AAC -0.14 0.0002
mRNA H2AFX CTRPv2 pan-cancer AAC 0.14 0.0002
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