RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACSM1	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ACSM3	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ACSS2	CTRPv2	pan-cancer	AAC	0.093	0.01
mRNA	ACTB	CTRPv2	pan-cancer	AAC	-0.12	0.001
mRNA	ACTN1	CTRPv2	pan-cancer	AAC	-0.14	0.0004
mRNA	ACTR5	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	ACVR1B	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ACVRL1	CTRPv2	pan-cancer	AAC	0.098	0.01
mRNA	ACY1	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	ADAM15	CTRPv2	pan-cancer	AAC	0.099	0.009

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