RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CNNM3	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	CMC4	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	PLCXD1	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	CCL15	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	BORCS7-ASMT	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	NARFL	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	ACTR5	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	PLXNB2	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	FRMD1	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	OTOF	CTRPv2	pan-cancer	AAC	0.12	0.0003

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