RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FZD5	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	ALKBH8	CTRPv2	pan-cancer	AAC	-0.13	0.0002
mRNA	CCL14	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	ZNRF2	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	NNAT	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	ZNF517	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	BAHD1	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	ZNF579	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	IFT52	CTRPv2	pan-cancer	AAC	-0.13	0.0003
mRNA	UBE2I	CTRPv2	pan-cancer	AAC	0.13	0.0003

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