RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KMT5C	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ZCCHC9	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	KLC2	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	LRRC24	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	CDX1	CTRPv2	pan-cancer	AAC	0.16	0.0002
mRNA	TOMM34	CTRPv2	pan-cancer	AAC	-0.14	0.0002
mRNA	COL20A1	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	PANK1	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	EPHX2	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	SETD1B	CTRPv2	pan-cancer	AAC	0.14	0.0002

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