RITA

Synonyms

Sources	Names Used
CTRPv2	RITA
PharmacoGx	RITA

External IDs

Database	Identifier
Smiles:	C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO
Inchikey:	KZENBFUSKMWCJF-UHFFFAOYSA-N
Pubchem:	374536

Annotated Targets

MDM2, TP53

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to RITA

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MIA3	CTRPv2	pan-cancer	AAC	0.15	6e-05
mRNA	UBR3	CTRPv2	pan-cancer	AAC	0.14	6e-05
mRNA	CBX2	CTRPv2	pan-cancer	AAC	0.16	7e-05
mRNA	CLDN15	CTRPv2	pan-cancer	AAC	0.15	7e-05
mRNA	CASP10	CTRPv2	pan-cancer	AAC	0.16	7e-05
mRNA	SLC2A4	CTRPv2	pan-cancer	AAC	0.14	7e-05
mRNA	ANKRD16	CTRPv2	pan-cancer	AAC	0.15	7e-05
mRNA	EPX	CTRPv2	pan-cancer	AAC	0.14	7e-05
mRNA	LGALS2	CTRPv2	pan-cancer	AAC	0.14	7e-05
mRNA	BCL2A1	CTRPv2	pan-cancer	AAC	-0.15	8e-05

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