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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HEXDC	CTRPv2	pan-cancer	AAC	0.082	0.04
mRNA	CD22	CTRPv2	pan-cancer	AAC	-0.08	0.04
mRNA	NR5A1	CTRPv2	pan-cancer	AAC	-0.075	0.04
mRNA	STAT3	CTRPv2	pan-cancer	AAC	-0.077	0.04
mRNA	ZPR1	CTRPv2	pan-cancer	AAC	-0.077	0.04
mRNA	ZFP2	CTRPv2	pan-cancer	AAC	0.077	0.04
mRNA	ENAH	CTRPv2	pan-cancer	AAC	0.086	0.04
mRNA	MZB1	CTRPv2	pan-cancer	AAC	0.086	0.04
mRNA	MTMR12	CTRPv2	pan-cancer	AAC	-0.076	0.04
mRNA	FAM161A	CTRPv2	pan-cancer	AAC	0.078	0.04

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