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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LILRA5	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	RP13-210D15.4	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ARHGAP12	CTRPv2	pan-cancer	AAC	-0.17	0.0001
mRNA	CDH24	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CLEC10A	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	AADACL2	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	SLC8A2	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ITSN2	CTRPv2	pan-cancer	AAC	-0.16	0.0001
mRNA	ATP13A4	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	HSH2D	CTRPv2	pan-cancer	AAC	0.16	0.0002

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