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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C2orf71	CTRPv2	pan-cancer	AAC	0.14	8e-05
mRNA	PLAC8	CTRPv2	pan-cancer	AAC	0.15	8e-05
mRNA	C19orf35	CTRPv2	pan-cancer	AAC	0.15	8e-05
mRNA	AKT3	CTRPv2	pan-cancer	AAC	0.14	8e-05
mRNA	RP11-1212A22.4	CTRPv2	pan-cancer	AAC	0.16	9e-05
mRNA	UBTFL1	CTRPv2	pan-cancer	AAC	0.14	9e-05
mRNA	TGM5	CTRPv2	pan-cancer	AAC	0.14	9e-05
mRNA	ZBTB18	CTRPv2	pan-cancer	AAC	0.15	9e-05
mRNA	LY6H	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	NLRP3	CTRPv2	pan-cancer	AAC	0.15	0.0001

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