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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RP11-475E11.9	CTRPv2	pan-cancer	AAC	0.12	0.0008
mRNA	CYBB	CTRPv2	pan-cancer	AAC	0.13	0.0008
mRNA	GOLGA8T	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	GPR26	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	PDE3B	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	DISP3	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	RILP	CTRPv2	pan-cancer	AAC	-0.12	0.0009
mRNA	REEP1	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	ST8SIA4	CTRPv2	pan-cancer	AAC	0.15	0.0009
mRNA	TM9SF3	CTRPv2	pan-cancer	AAC	-0.13	0.0009

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