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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RAB3D	CTRPv2	pan-cancer	AAC	0.14	0.0005
mRNA	NPAS4	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	AMY1B	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	GPR171	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	NNAT	CTRPv2	pan-cancer	AAC	0.12	0.0005
mRNA	AKAP5	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	EFCAB10	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	BANK1	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	LPP	CTRPv2	pan-cancer	AAC	-0.13	0.0005
mRNA	PRDM13	CTRPv2	pan-cancer	AAC	0.13	0.0005

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