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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	WDR64	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	SIGLEC7	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	C17orf64	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	ATP2B3	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	SERPINB12	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	SNCB	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	LRFN5	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	LEFTY2	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	CHODL	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	FGFR3	CTRPv2	pan-cancer	AAC	0.13	0.0003

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