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AM-580

AM-580

Synonyms

Sources	Names Used
CTRPv2	AM-580
PharmacoGx	AM-580

External IDs

Database	Identifier
Smiles:	CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C
Inchikey:	SZWKGOZKRMMLAJ-UHFFFAOYSA-N
Pubchem:	2126

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AM-580

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GK2	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	ABHD15	CTRPv2	pan-cancer	AAC	0.14	0.0002
mRNA	ZHX1	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	WAS	CTRPv2	pan-cancer	AAC	0.24	0.0003
mRNA	CPO	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	HLX	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	MEF2D	CTRPv2	pan-cancer	AAC	0.15	0.0003
mRNA	OTX2	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	PDE1A	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	SH3GL2	CTRPv2	pan-cancer	AAC	0.13	0.0003

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