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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KAT8	CTRPv2	pan-cancer	AAC	0.21	3e-08
mRNA	KIAA1958	CTRPv2	pan-cancer	AAC	0.22	4e-08
mRNA	RBBP4	CTRPv2	pan-cancer	AAC	0.23	4e-08
mRNA	CTCF	CTRPv2	pan-cancer	AAC	0.23	4e-08
mRNA	THAP9	CTRPv2	pan-cancer	AAC	0.21	4e-08
mRNA	GKAP1	CTRPv2	pan-cancer	AAC	0.2	4e-08
mRNA	NPIPA1	CTRPv2	pan-cancer	AAC	0.21	4e-08
mRNA	FUZ	CTRPv2	pan-cancer	AAC	0.21	5e-08
mRNA	ATP6V1G2	CTRPv2	pan-cancer	AAC	0.22	5e-08
mRNA	C12orf57	CTRPv2	pan-cancer	AAC	0.2	5e-08

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