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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRKCQ	CTRPv2	pan-cancer	AAC	0.22	1e-08
mRNA	ILF3	CTRPv2	pan-cancer	AAC	0.23	1e-08
mRNA	ZNF738	CTRPv2	pan-cancer	AAC	0.21	2e-08
mRNA	MEX3A	CTRPv2	pan-cancer	AAC	0.25	2e-08
mRNA	RCC2	CTRPv2	pan-cancer	AAC	0.23	2e-08
mRNA	RFX7	CTRPv2	pan-cancer	AAC	0.23	2e-08
mRNA	USP7	CTRPv2	pan-cancer	AAC	0.21	2e-08
mRNA	SMIM8	CTRPv2	pan-cancer	AAC	0.21	3e-08
mRNA	DCK	CTRPv2	pan-cancer	AAC	0.24	3e-08
mRNA	KIF22	CTRPv2	pan-cancer	AAC	0.21	3e-08

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