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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF724	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ZNF730	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	ZNF736	CTRPv2	pan-cancer	AAC	0.17	3e-05
mRNA	ZNF737	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ZNF738	CTRPv2	pan-cancer	AAC	0.21	2e-08
mRNA	ZNF747	CTRPv2	pan-cancer	AAC	0.16	9e-06
mRNA	ZNF764	CTRPv2	pan-cancer	AAC	0.18	5e-07
mRNA	ZNF766	CTRPv2	pan-cancer	AAC	0.14	0.0003
mRNA	ZNF77	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ZNF771	CTRPv2	pan-cancer	AAC	0.18	1e-06

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