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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CFAP77	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	NLK	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	GSTA4	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	KAT6A	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ZBTB8B	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ANXA2R	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	TOMM7	CTRPv2	pan-cancer	AAC	-0.12	0.003
mRNA	CD72	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	KYAT3	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ZNF580	CTRPv2	pan-cancer	AAC	0.11	0.003

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