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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IQCB1	CTRPv2	pan-cancer	AAC	0.13	0.003
mRNA	FAM53B	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	FAM181B	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	NCR3LG1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	HSPA1B	CTRPv2	pan-cancer	AAC	-0.12	0.003
mRNA	RCSD1	CTRPv2	pan-cancer	AAC	0.14	0.003
mRNA	XRCC1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	MAP3K15	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	FANCC	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	R3HDM2	CTRPv2	pan-cancer	AAC	0.11	0.003

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