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RG-108

RG-108

Synonyms

Sources	Names Used
CTRPv2	RG-108
PharmacoGx	RG-108

External IDs

Database	Identifier
Smiles:	C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
Inchikey:	HPTXLHAHLXOAKV-UHFFFAOYSA-N
Pubchem:	344265

Annotated Targets

DNMT1, DNMT3B

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to RG-108

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PAQR4	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	ZNF518A	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	FZD3	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	FAM216A	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	LRIT1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	UBTD1	CTRPv2	pan-cancer	AAC	-0.13	0.003
mRNA	AK8	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	SAMD14	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	TCEANC2	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	HIST1H4H	CTRPv2	pan-cancer	AAC	-0.11	0.003

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