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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	CACNA1B	CTRPv2	pan-cancer	AAC	0.2	7e-09
mRNA	ZNF397	CTRPv2	pan-cancer	AAC	0.19	7e-09
mRNA	TIA1	CTRPv2	pan-cancer	AAC	0.19	8e-09
mRNA	CBX2	CTRPv2	pan-cancer	AAC	0.2	8e-09
mRNA	PRR36	CTRPv2	pan-cancer	AAC	0.19	8e-09
mRNA	SH2D3C	CTRPv2	pan-cancer	AAC	0.22	9e-09
mRNA	GNAZ	CTRPv2	pan-cancer	AAC	0.18	9e-09
mRNA	ADAM22	CTRPv2	pan-cancer	AAC	0.2	9e-09
mRNA	ZNF646	CTRPv2	pan-cancer	AAC	0.19	1e-08
mRNA	TRAPPC2	CTRPv2	pan-cancer	AAC	0.19	1e-08

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