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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZSWIM4	CTRPv2	pan-cancer	AAC	0.12	0.0001
mRNA	ZSCAN30	CTRPv2	pan-cancer	AAC	0.12	0.0002
mRNA	ZSCAN29	CTRPv2	pan-cancer	AAC	0.13	0.0002
mRNA	ZSCAN25	CTRPv2	pan-cancer	AAC	0.13	3e-05
mRNA	ZSCAN21	CTRPv2	pan-cancer	AAC	0.1	0.001
mRNA	ZSCAN16	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	ZPR1	CTRPv2	pan-cancer	AAC	-0.12	9e-05
mRNA	ZNRF2	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	ZNRD1	CTRPv2	pan-cancer	AAC	-0.12	0.0006
mRNA	ZNF92	CTRPv2	pan-cancer	AAC	0.18	2e-08

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