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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	AGAP2	CTRPv2	pan-cancer	AAC	0.22	6e-08
mRNA	KMT2C	CTRPv2	pan-cancer	AAC	0.22	1e-11
mRNA	FCHSD2	CTRPv2	pan-cancer	AAC	0.22	9e-10
mRNA	CD38	CTRPv2	pan-cancer	AAC	0.22	3e-11
mRNA	PPM1E	CTRPv2	pan-cancer	AAC	0.23	6e-11
mRNA	ZFHX2	CTRPv2	pan-cancer	AAC	0.23	8e-11
mRNA	ZNF107	CTRPv2	pan-cancer	AAC	0.23	2e-11
mRNA	TCF3	CTRPv2	pan-cancer	AAC	0.23	5e-10
mRNA	AKNA	CTRPv2	pan-cancer	AAC	0.23	2e-08
mRNA	ZNF253	CTRPv2	pan-cancer	AAC	0.23	2e-12

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