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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EGF	CTRPv2	pan-cancer	AAC	-0.11	0.001
mRNA	RNF112	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	C2orf81	CTRPv2	pan-cancer	AAC	0.1	0.001
mRNA	MCFD2	CTRPv2	pan-cancer	AAC	-0.11	0.001
mRNA	DCC	CTRPv2	pan-cancer	AAC	0.099	0.001
mRNA	CLASP2	CTRPv2	pan-cancer	AAC	0.12	0.001
mRNA	ZFP90	CTRPv2	pan-cancer	AAC	0.1	0.001
mRNA	FAM227A	CTRPv2	pan-cancer	AAC	0.1	0.001
mRNA	DNAJC27	CTRPv2	pan-cancer	AAC	0.1	0.001
mRNA	GFI1B	CTRPv2	pan-cancer	AAC	-0.099	0.001

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