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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPTBN4	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	TMEM179	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	KLF1	CTRPv2	pan-cancer	AAC	-0.11	0.0004
mRNA	DHX9	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	GRAP	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	RHCE	CTRPv2	pan-cancer	AAC	-0.11	0.0004
mRNA	EP400	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	CAMK2N2	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	TMEM94	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	ARHGAP19-SLIT1	CTRPv2	pan-cancer	AAC	0.13	0.0004

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