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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KCNJ4	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	SMAD1	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	ABCC8	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	SMARCD1	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	KCNN1	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	LHX2	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	OLA1	CTRPv2	pan-cancer	AAC	-0.11	0.0004
mRNA	GTF3C4	CTRPv2	pan-cancer	AAC	0.11	0.0004
mRNA	REXO1	CTRPv2	pan-cancer	AAC	0.12	0.0004
mRNA	RIMBP2	CTRPv2	pan-cancer	AAC	0.13	0.0004

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