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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PLCL2	CTRPv2	pan-cancer	AAC	0.2	6e-08
mRNA	IDH2	CTRPv2	pan-cancer	AAC	0.18	6e-08
mRNA	USP49	CTRPv2	pan-cancer	AAC	0.18	7e-08
mRNA	ABHD17B	CTRPv2	pan-cancer	AAC	0.18	7e-08
mRNA	RP11-637O19.3	CTRPv2	pan-cancer	AAC	-0.17	7e-08
mRNA	SETD1A	CTRPv2	pan-cancer	AAC	0.18	7e-08
mRNA	ARID1A	CTRPv2	pan-cancer	AAC	0.19	7e-08
mRNA	RBM6	CTRPv2	pan-cancer	AAC	0.18	7e-08
mRNA	MBTD1	CTRPv2	pan-cancer	AAC	0.2	7e-08
mRNA	UBR7	CTRPv2	pan-cancer	AAC	0.17	8e-08

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