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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SAP30L	CTRPv2	pan-cancer	AAC	0.13	2e-05
mRNA	DUSP28	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	ZNF250	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	ATRX	CTRPv2	pan-cancer	AAC	0.13	2e-05
mRNA	GRK4	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	PANX2	CTRPv2	pan-cancer	AAC	-0.14	2e-05
mRNA	CYP4F11	CTRPv2	pan-cancer	AAC	-0.14	2e-05
mRNA	PIAS4	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	ZFX	CTRPv2	pan-cancer	AAC	0.13	2e-05
mRNA	CACNB3	CTRPv2	pan-cancer	AAC	0.14	2e-05

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