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prima-1

prima-1

Synonyms

Sources	Names Used
CTRPv2	PRIMA-1
PharmacoGx	prima-1

External IDs

Database	Identifier
Smiles:	C1CN2CCC1C(=O)C2(CO)CO
Inchikey:	RFBVBRVVOPAAFS-UHFFFAOYSA-N
Pubchem:	322968

Annotated Targets

ACHE, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to prima-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KIF1A	CTRPv2	pan-cancer	AAC	0.2	2e-09
mRNA	CTCF	CTRPv2	pan-cancer	AAC	0.21	2e-09
mRNA	TMSB15B	CTRPv2	pan-cancer	AAC	0.19	2e-09
mRNA	TRIM16L	CTRPv2	pan-cancer	AAC	-0.2	3e-09
mRNA	PARP1	CTRPv2	pan-cancer	AAC	0.21	3e-09
mRNA	ZNF142	CTRPv2	pan-cancer	AAC	0.2	3e-09
mRNA	BCL7A	CTRPv2	pan-cancer	AAC	0.2	3e-09
mRNA	UBTF	CTRPv2	pan-cancer	AAC	0.2	3e-09
mRNA	USP42	CTRPv2	pan-cancer	AAC	0.19	3e-09
mRNA	BSN	CTRPv2	pan-cancer	AAC	0.22	3e-09

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