1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ADAM9 GDSC1000 pan-cancer AAC -0.26 5e-10
mRNA MED12 GDSC1000 pan-cancer AAC 0.2 5e-10
mRNA ARRB2 GDSC1000 pan-cancer AAC 0.2 5e-10
mRNA ANKRD46 GDSC1000 pan-cancer AAC 0.21 5e-10
mRNA UBN2 GDSC1000 pan-cancer AAC 0.2 5e-10
mRNA DYRK1A GDSC1000 pan-cancer AAC 0.22 5e-10
mRNA ICE2 GDSC1000 pan-cancer AAC 0.2 6e-10
mRNA SMIM24 GDSC1000 pan-cancer AAC 0.2 6e-10
mRNA ATAD5 GDSC1000 pan-cancer AAC 0.22 6e-10
mRNA ATAD2B GDSC1000 pan-cancer AAC 0.22 6e-10
Download CSV