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GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA UGT3A2 GDSC1000 pan-cancer AAC 0.32 7e-19
mRNA YPEL1 GDSC1000 pan-cancer AAC 0.3 8e-19
mRNA RAVER2 GDSC1000 pan-cancer AAC 0.28 1e-18
mRNA MYO1C GDSC1000 pan-cancer AAC -0.35 2e-18
mRNA GPC2 GDSC1000 pan-cancer AAC 0.3 3e-18
mRNA TMBIM1 GDSC1000 pan-cancer AAC -0.32 3e-18
mRNA WASF1 GDSC1000 pan-cancer AAC 0.3 4e-18
mRNA RBBP4 GDSC1000 pan-cancer AAC 0.28 7e-18
mRNA MSL2 GDSC1000 pan-cancer AAC 0.33 9e-18
mRNA BCL11A GDSC1000 pan-cancer AAC 0.3 2e-17
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