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GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA GPATCH8 GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA WDR33 GDSC1000 pan-cancer AAC 0.2 6e-08
mRNA CLIC2 GDSC1000 pan-cancer AAC -0.17 6e-08
mRNA HAUS6 GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA MCM7 GDSC1000 pan-cancer AAC 0.17 6e-08
mRNA GFI1 GDSC1000 pan-cancer AAC 0.22 6e-08
mRNA GNG12 GDSC1000 pan-cancer AAC -0.25 6e-08
mRNA EBF3 GDSC1000 pan-cancer AAC 0.18 7e-08
mRNA RAB9A GDSC1000 pan-cancer AAC -0.17 7e-08
mRNA ZNF439 GDSC1000 pan-cancer AAC 0.18 7e-08
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