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GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF124 GDSC1000 pan-cancer AAC 0.28 3e-15
mRNA BLVRB GDSC1000 pan-cancer AAC -0.26 3e-15
mRNA NCKAP1L GDSC1000 pan-cancer AAC 0.4 4e-15
mRNA FUCA2 GDSC1000 pan-cancer AAC -0.28 6e-15
mRNA MYOF GDSC1000 pan-cancer AAC -0.32 7e-15
mRNA TNFRSF12A GDSC1000 pan-cancer AAC -0.35 8e-15
mRNA MFAP4 GDSC1000 pan-cancer AAC 0.27 9e-15
mRNA MTF2 GDSC1000 pan-cancer AAC 0.28 9e-15
mRNA LAIR1 GDSC1000 pan-cancer AAC 0.32 1e-14
mRNA HDAC2 GDSC1000 pan-cancer AAC 0.26 1e-14
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