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GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA TMEM214 GDSC1000 pan-cancer AAC -0.18 2e-08
mRNA KCNAB3 GDSC1000 pan-cancer AAC 0.19 2e-08
mRNA SGCE GDSC1000 pan-cancer AAC -0.21 2e-08
mRNA DAZAP1 GDSC1000 pan-cancer AAC 0.2 2e-08
mRNA ASPH GDSC1000 pan-cancer AAC -0.22 2e-08
mRNA OTUD7B GDSC1000 pan-cancer AAC -0.19 2e-08
mRNA CLEC11A GDSC1000 pan-cancer AAC 0.19 2e-08
mRNA KDM2B GDSC1000 pan-cancer AAC 0.22 2e-08
mRNA TSPAN4 GDSC1000 pan-cancer AAC -0.21 2e-08
mRNA HCFC1R1 GDSC1000 pan-cancer AAC -0.2 2e-08
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