1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ZCCHC3 GDSC1000 pan-cancer AAC 0.21 2e-09
mRNA ZNF254 GDSC1000 pan-cancer AAC 0.2 2e-09
mRNA GAL3ST4 GDSC1000 pan-cancer AAC 0.19 2e-09
mRNA ADNP2 GDSC1000 pan-cancer AAC 0.19 2e-09
mRNA SALL2 GDSC1000 pan-cancer AAC 0.21 2e-09
mRNA PTBP1 GDSC1000 pan-cancer AAC 0.2 2e-09
mRNA RTN4R GDSC1000 pan-cancer AAC 0.19 2e-09
mRNA YEATS2 GDSC1000 pan-cancer AAC 0.19 2e-09
mRNA SLC35D2 GDSC1000 pan-cancer AAC -0.25 2e-09
mRNA YIPF5 GDSC1000 pan-cancer AAC -0.21 2e-09
Download CSV