1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA C1orf228 GDSC1000 pan-cancer AAC 0.22 6e-10
mRNA KDM5B GDSC1000 pan-cancer AAC 0.21 6e-10
mRNA KIAA1958 GDSC1000 pan-cancer AAC 0.21 7e-10
mRNA SCAF8 GDSC1000 pan-cancer AAC 0.2 7e-10
mRNA SUMF1 GDSC1000 pan-cancer AAC -0.21 7e-10
mRNA B4GALT7 GDSC1000 pan-cancer AAC -0.2 7e-10
mRNA UBE2H GDSC1000 pan-cancer AAC -0.21 7e-10
mRNA SH3BP5 GDSC1000 pan-cancer AAC -0.2 7e-10
mRNA DPH3 GDSC1000 pan-cancer AAC -0.2 7e-10
mRNA KLHL8 GDSC1000 pan-cancer AAC 0.22 8e-10
Download CSV