1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA CTCF GDSC1000 pan-cancer AAC 0.23 2e-10
mRNA HNRNPD GDSC1000 pan-cancer AAC 0.22 2e-10
mRNA SMARCA4 GDSC1000 pan-cancer AAC 0.21 2e-10
mRNA SLC12A4 GDSC1000 pan-cancer AAC -0.21 2e-10
mRNA NRF1 GDSC1000 pan-cancer AAC 0.22 2e-10
mRNA UBE3D GDSC1000 pan-cancer AAC 0.22 2e-10
mRNA FOXJ3 GDSC1000 pan-cancer AAC 0.2 2e-10
mRNA CECR6 GDSC1000 pan-cancer AAC 0.2 3e-10
mRNA ZAP70 GDSC1000 pan-cancer AAC 0.21 3e-10
mRNA GDF11 GDSC1000 pan-cancer AAC 0.22 3e-10
Download CSV