1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA WDR5 GDSC1000 pan-cancer AAC 0.2 9e-11
mRNA SUGP1 GDSC1000 pan-cancer AAC 0.22 1e-10
mRNA CELF5 GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA P2RX1 GDSC1000 pan-cancer AAC 0.24 1e-10
mRNA UPF3B GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA NELL2 GDSC1000 pan-cancer AAC 0.23 1e-10
mRNA BCLAF1 GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA TGOLN2 GDSC1000 pan-cancer AAC -0.22 1e-10
mRNA SLC7A3 GDSC1000 pan-cancer AAC 0.21 1e-10
mRNA DUSP5 GDSC1000 pan-cancer AAC -0.21 1e-10
Download CSV