1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA SRSF11 GDSC1000 pan-cancer AAC 0.22 7e-11
mRNA LTBR GDSC1000 pan-cancer AAC -0.26 7e-11
mRNA TRAM2 GDSC1000 pan-cancer AAC -0.23 8e-11
mRNA UGDH GDSC1000 pan-cancer AAC -0.22 8e-11
mRNA CD55 GDSC1000 pan-cancer AAC -0.22 8e-11
mRNA ZNF202 GDSC1000 pan-cancer AAC 0.21 8e-11
mRNA NAMPT GDSC1000 pan-cancer AAC -0.2 8e-11
mRNA TAF5 GDSC1000 pan-cancer AAC 0.23 9e-11
mRNA AIF1 GDSC1000 pan-cancer AAC 0.24 9e-11
mRNA SCAF4 GDSC1000 pan-cancer AAC 0.23 9e-11
Download CSV