1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA HDHD2 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA PRPF3 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA YKT6 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA DNAJC10 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA ANXA4 GDSC1000 pan-cancer AAC -0.16 5e-05
mRNA FN1 GDSC1000 pan-cancer AAC -0.16 5e-05
mRNA MTBP GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA USF3 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA ISCU GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA TENM4 GDSC1000 pan-cancer AAC 0.14 5e-05
Download CSV