1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA PARP1 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA CLK2 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA SIDT2 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA IFITM3 GDSC1000 pan-cancer AAC -0.16 5e-05
mRNA PGAP1 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA GMEB1 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA SSRP1 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA CEP350 GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA IZUMO4 GDSC1000 pan-cancer AAC -0.14 5e-05
mRNA FAM129B GDSC1000 pan-cancer AAC -0.2 5e-05
Download CSV