1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF451 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA NFKBIA GDSC1000 pan-cancer AAC -0.14 4e-05
mRNA C19orf57 GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA ASS1 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA MKRN3 GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA MIS18A GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA SIRT1 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA MRFAP1L1 GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA MCM9 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA TSPYL4 GDSC1000 pan-cancer AAC 0.14 4e-05
Download CSV