1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA SMAD9 GDSC1000 pan-cancer AAC 0.14 3e-05
mRNA NR3C1 GDSC1000 pan-cancer AAC -0.16 3e-05
mRNA ZNF790 GDSC1000 pan-cancer AAC 0.13 3e-05
mRNA MAGT1 GDSC1000 pan-cancer AAC -0.13 3e-05
mRNA RNASEH2A GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA CNOT2 GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA TSPAN17 GDSC1000 pan-cancer AAC -0.15 4e-05
mRNA DDX49 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA POLR2B GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA DGCR8 GDSC1000 pan-cancer AAC 0.13 4e-05
Download CSV