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GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF121 GDSC1000 pan-cancer AAC 0.22 7e-12
mRNA SGMS1 GDSC1000 pan-cancer AAC -0.23 8e-12
mRNA AGO4 GDSC1000 pan-cancer AAC 0.22 8e-12
mRNA AMFR GDSC1000 pan-cancer AAC -0.21 8e-12
mRNA RELB GDSC1000 pan-cancer AAC -0.22 8e-12
mRNA NUP160 GDSC1000 pan-cancer AAC 0.22 9e-12
mRNA NDFIP1 GDSC1000 pan-cancer AAC -0.21 9e-12
mRNA CTSZ GDSC1000 pan-cancer AAC -0.23 9e-12
mRNA EZH2 GDSC1000 pan-cancer AAC 0.24 9e-12
mRNA ICAM1 GDSC1000 pan-cancer AAC -0.22 1e-11
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