1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ADNP GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA RAB22A GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA ANP32A GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA HIRA GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA TDG GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA CST3 GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA PAK5 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA BRE GDSC1000 pan-cancer AAC -0.13 2e-05
mRNA CCR9 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA VASH2 GDSC1000 pan-cancer AAC 0.14 2e-05
Download CSV