1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF320 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA UBTD1 GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA SHISA5 GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA RSRC2 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA SUOX GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA ZNF140 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA C9orf40 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA PLPPR1 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA C6orf89 GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA GCLM GDSC1000 pan-cancer AAC -0.14 2e-05
Download CSV