1. Home/
  2. Compounds/
  3. GSK1070916

GSK1070916

Synonyms

SourcesNames Used
GDSC1000, GRAYGSK1070916
PharmacoGx GSK1070916

External IDs

DatabaseIdentifier
Smiles: CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
Inchikey: QTBWCSQGBMPECM-UHFFFAOYSA-N
Pubchem: 46885626

Annotated Targets

AURKA, AURKB, AURKC, CYP2D6, CYP3A4

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to GSK1070916


Feature TypeStandardized
Nominal ANOVA
mRNA SERTAD2 GDSC1000 pan-cancer AAC -0.14 1e-05
mRNA ASAH1 GDSC1000 pan-cancer AAC -0.14 1e-05
mRNA FKBP9 GDSC1000 pan-cancer AAC -0.16 1e-05
mRNA BCAR1 GDSC1000 pan-cancer AAC -0.16 1e-05
mRNA USP11 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA GCNT2 GDSC1000 pan-cancer AAC -0.14 1e-05
mRNA RORB GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA C1orf54 GDSC1000 pan-cancer AAC 0.16 1e-05
mRNA SNRPD1 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA KMT2E GDSC1000 pan-cancer AAC 0.14 1e-05
Download CSV