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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA DCC CCLE pan-cancer AAC 0.22 3e-06
mRNA EBF1 CCLE pan-cancer AAC -0.24 3e-06
mRNA CD69 CCLE pan-cancer AAC -0.25 4e-06
mRNA ARNT CCLE pan-cancer AAC 0.23 4e-06
mRNA C9orf66 CCLE pan-cancer AAC 0.22 5e-06
mRNA TCL1A CCLE pan-cancer AAC -0.23 5e-06
mRNA SCARB2 CCLE pan-cancer AAC 0.23 5e-06
mRNA ERN1 CCLE pan-cancer AAC 0.22 5e-06
mRNA ENPP6 CCLE pan-cancer AAC 0.2 5e-06
mRNA SLAMF6 CCLE pan-cancer AAC -0.25 5e-06
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