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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA SESN1 CCLE pan-cancer AAC 0.22 5e-06
mRNA CD81 CCLE pan-cancer AAC -0.22 6e-06
mRNA PRDM1 CCLE pan-cancer AAC 0.22 6e-06
mRNA C11orf71 CCLE pan-cancer AAC 0.21 6e-06
mRNA CD37 CCLE pan-cancer AAC -0.3 6e-06
mRNA MCOLN2 CCLE pan-cancer AAC -0.22 6e-06
mRNA CDC20 CCLE pan-cancer AAC -0.21 6e-06
mRNA AIM1 CCLE pan-cancer AAC -0.22 7e-06
mRNA MAF CCLE pan-cancer AAC 0.22 7e-06
mRNA ANKDD1A CCLE pan-cancer AAC 0.21 7e-06
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